For U.S. Residents Only
See your advanced prostate cancer treatment
in a different light.
JEVTANA is a prescription anti-cancer medicine used with the steroid medicine prednisone to treat people with prostate cancer that has worsened (progressed) after treatment with other anti-cancer medicines, including docetaxel. It is not known if JEVTANA is safe
and effective in children.
JEVTANA is not for use in females.


JEVTANA may fight tumors that have become resistant to docetaxel, so it may help you even if docetaxel is no longer working.

Learn more

Questions for Your Healthcare Provider

Ask your healthcare team any questions you have about JEVTANA and your advanced prostate cancer treatment plan. Remember, each man's experience is different. Learn more


What is the most important information I should know about JEVTANA (cabazitaxel)?
JEVTANA may cause serious side effects, including:

Low white blood cells can cause you to get serious infections, and may lead to death. People who are 65 years or older may be more likely to have these problems. Your healthcare provider (HCP):

Tell your HCP right away if you have any of these symptoms of infection during treatment with JEVTANA: fever (take your temperature often during treatment with JEVTANA), cough, burning on urination, or muscle aches.
Also, tell your HCP if you have any diarrhea during the time that your white blood cell count is low. Your HCP may prescribe treatment for you as needed.
Severe allergic reactions can happen within a few minutes after your infusion of JEVTANA starts, especially during the first and second infusions. Your HCP should prescribe medicines before each infusion to help prevent severe allergic reactions.

Tell your HCP or nurse right away if you have any of these symptoms of a severe allergic reaction during or soon after an infusion of JEVTANA: rash or itching, skin redness, feeling dizzy or faint, breathing problems, chest or throat tightness, or swelling of face.

JEVTANA can cause severe stomach and intestine (gastrointestinal) problems, which may lead to death. You may need to go to the hospital for treatment.

Vomiting and diarrhea can happen when you receive JEVTANA. Severe vomiting and diarrhea with JEVTANA can lead to loss of too much body fluid (dehydration), or too much of your body salts (electrolytes). Death has happened from having severe diarrhea and losing too much body fluid or body salts with JEVTANA. Your HCP will prescribe medicines to prevent or treat vomiting and diarrhea, as needed with JEVTANA.

Tell your HCP if: you have vomiting or diarrhea, or if your symptoms get worse or do not get better.

JEVTANA can cause a leak in the stomach or intestine, intestinal blockage, infection, and bleeding in the stomach or intestine. This can lead to death. Tell your HCP if you get any of these symptoms: severe stomach-area (abdomen) pain, constipation, fever, blood in your stool, or changes in the color of your stool.

Kidney failure may happen with JEVTANA, because of severe infection, loss of too much body fluid (dehydration), and other reasons, which may lead to death. Your HCP will check you for this problem and treat you if needed.

Tell your HCP if you develop these signs or symptoms: swelling of your face or body, or decrease in the amount of urine that your body makes each day.

Lung or breathing problems may happen with JEVTANA and may lead to death. People who have lung disease before receiving JEVTANA may have a higher risk for developing lung or breathing problems with JEVTANA treatment. Your HCP will check you for this problem and treat you if needed.

Tell your HCP right away if you develop any new or worsening symptoms, including: trouble breathing, shortness of breath, chest pain cough or fever.

Who should not receive JEVTANA Injection?

Do not receive JEVTANA if: your white blood cell (neutrophil count) is too low, you have had a severe allergic reaction to cabazitaxel or other medicines that contain polysorbate 80 (ask your HCP if you are not sure), or you have severe liver problems.

What should I tell my HCP before receiving JEVTANA?

Before receiving JEVTANA, tell your HCP if you: had allergic reactions in the past, have kidney or liver problems, have lung problems, are age 65 or older, have any other medical conditions, or are female and

Tell your HCP about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. JEVTANA can interact with many other medicines. Do not take any new medicines without asking your HCP first. Your HCP will tell you if it is safe to take the new medicine with JEVTANA.

What are the possible side effects of JEVTANA?

Common side effects of JEVTANA include:

  • tiredness
  • nausea
  • constipation
  • weakness
  • blood in your urine. Tell your HCP or nurse if you see blood in your urine.
  • back pain
  • shortness of breath
  • stomach (abdominal) pain
  • change in your sense of taste
  • cough
  • joint pain
  • hair loss
  • decreased appetite

Tell your HCP if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of JEVTANA. For more information, ask your HCP or pharmacist.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See Full Prescribing Information.